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Apr 19, 2024
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MICR 453 - Immunology (3 units)
Organization, development, and regulation of the immune system, antibody structure and function, cellular and humoral effector mechanisms in immunity, and immunologic mechanisms in disease. (Formerly BIOL 460 R/660 R; implemented Spring 2006.)
Prerequisite(s): BIOL 300 or BIOL 315 .
Units of Lecture: 3
Offered: Every Fall
Student Learning Outcomes:
Upon completion of this course:
1. Students will be able to recognize the various innate immune mechanisms that provide initial defense against pathogenic organisms.
2. Students will be able to describe how innate immunity provides the signals for initiating adaptive immunity.
3. Students will be able to describe the development of T and B lymphocytes, and explain the genetic basis for generation of antigen receptor diversity.
4. Students will be able to compare and contrast the recognition of antigen by T and B lymphocytes, and define the role of the major histocompatibility complex.
5. Students will be able to discuss the role of cell-mediated and humoral immune defense mechanisms against pathogens.
6. Students will be able to describe how microbes avoid immune defenses, and describe various primary and acquired immunodeficiencies.
7. Students will be able to demonstrate understanding of the principles of allergy and hypersensitivity diseases, autoimmunity, transplantation, immunoregulation, tumor immunology, and vaccination.
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