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Apr 23, 2024
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BIOL 653 - Immunology (3 units)
Organization, development, and regulation of the immune system, antibody structure and function, cellular and humoral effector mechanisms in immunity, and immunologic mechanisms in disease. (BIOL 653 and MICR 653 are cross-listed; credit may be earned in one of the two.)
Units of Lecture: 3
Offered: Every Fall
Student Learning Outcomes:
Upon completion of this course:
1. Students will be able to recognize the various innate immune mechanisms that provide initial defense against pathogenic organisms.
2. Students will be able to explain how innate immunity provides the signals for initiating adaptive immunity.
3. Students will be able to describe the development of T and B lymphocytes, and explain the genetic basis for generation of antigen receptor diversity.
4. Students will be able to compare and contrast the recognition of antigen by T and B lymphocytes, and define the role of the major histocompatibility complex.
5. Students will be able to discuss the role of cell-mediated and humoral immune defense mechanisms against pathogens.
6. Students will be able to explain how microbes avoid immune defenses, and describe various primary and acquired immunodeficiencies.
7. Students will be able to demonstrate an understanding of how the principles of allergy and hypersensitivity diseases, autoimmunity, transplantation, immunoregulation, tumor immunology, and vaccination.
8. Students will be able to prepare a research paper on a topic in basic or clinical immunology using recent references from the primary immunology research literature.
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